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Tissue Genesis’ Business

Tissue Genesis, Inc. seeks to advance tissue engineering and cell therapy solutions that save lives and improve the quality of life for patients with illness and disease. Tissue Genesis’ business strategy is to promote the use of a patients own adipose (fat) derived therapeutic cells in repairing damaged tissue and coating of implants. These cells can be delivered in a wound dressing, or can be delivered to damaged tissue by means of a catheter or direct injection, such as injection into damaged heart tissue. These therapeutic cells can also be coated onto implants, such as vascular grafts and stents. In addition to enabling these applications through its intellectual property, Tissue Genesis will manufacture operating room systems for the derivation of these cells from the patient’s adipose tissue during a medical procedure, leveraging the company’s versatile enabling platform technology, to add to the value chain for customers and their patients. Both our systems and these specific applications represent significant potential revenue streams for TGI.

Tissue Genesis was incorporated in the State of Hawaii in 2001 by founders Anton Krucky, Thomas Cannon and Bill Wiesmann, M.D. The company currently has 25 full time employees, including a team of five PhDs who conduct top tier research and development in bioengineering, vascular tissue engineering, musculoskeletal tissue engineering, cell therapy, and related regenerative medicine fields. In 2003, Tissue Genesis built a world class research facility in the newly developed Kaka‘ako Biomedical Park, site of the University of Hawaii’s new John A. Burns School of Medicine. Tissue Genesis’ facilities include office space; a 4200 square-foot Class A wet lab, and a 3200 square-foot pre-manufacturing area. Tissue Genesis is located in Honolulu, Hawaii and our website address is www.tissuegenesis.com.


Mission

Tissue Genesis, Inc. is an emerging high-growth company in the field of regenerative medicine, using a patient’s own therapeutic cells to coat implants, repair damaged tissue, heal disease, and other uses. Tissue Genesis is leveraging its perfusion platform and expertise to deliver products to the tissue engineering market. Current near term applications include vascular grafts and wound healing using patients’ own regenerative cells.


Highlights

Founded: In 2001, began operations 2002
Employees: 25 with five PhDs
Lead Products: Vascular Conduit Solutions, Wound Healing, Tissue Repair, BOS® Product Line
Intellectual Property:
  • Derivation and Use of Fat-Derived Autologous (Patient’s Own)Therapeutic Cells
  • Exclusive license of Dr. Stuart Williams’ pioneering patent portfolio from Thomas Jefferson University.
  • Connective Tissue Engineering
  • Exclusive license of Dr. Paul Kosnik’s patent portfolio from University of Michigan.
  • Bio-Optimization System (BOS) Line of Products
  • Patent applications pending.
  • Sustained Pressure Sodding of Implants Using Therapeutic Cells
  • Developed at Tissue Genesis – patents pending on advanced cell deposition technology and hardware.
    Ownership: Privately Held
    Funding: Capital Investment, Contracts and Grants
       

    Tissue Genesis, Inc. Product and Company Overview